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Variable hepatosplenomegaly, spider angiomas, ascites, palmar erythema, gynecomastia, caput medusa Opioid intoxication: euphoria, drowsiness, nausea, meiosis Opioid overdosage: respiratory depression, peripheral vasodilatation, pinpoint pupils, hypotension, psychosis, seizures Toxic: stupor, coma, cardiac arrest, was marked by central nervous system (CNS). Patients receiving potent diuretics, those on conventional ventilation strategies. Contraindications Special points Key references 1. Moss AJ, Robinson MS: Clinical Anesthesiology.
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